Rahmawati, Elizabeth (2022) GAMBARAN INTERAKSI OBAT AZITROMISIN PASIEN COVID-19 KOMORBID KARDIOVASKULER DI RS PANTI NIRMALA MALANG. Diploma Tiga (D3) thesis, ITSK RS dr. Soepraoen.
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Abstract
Interaksi obat merupakan efek dari suatu obat yang disebabkan jika terdapat dua obat atau lebih yang saling berinteraksi dan mempengaruhi respon tubuh terhadap pengobatan. Penelitian ini merupakan penelitian deskriptif menggunakan metode observasional non-eksperimental dengan pendekatan cross-sectional menggunakan pengamatan retrospektif dengan mengambil data pada bulan Desember 2020 – Agustus 2021. Pengambilan data pasien diperoleh dari data rekam medis pasien dengan teknik pengambilan sampel yaitu purposive sampling dengan kriteria inklusi sebanyak 43 pasien yang diambil sebagai sampel. Analisis data menggunakan aplikasi medscape dan drugs.com. Sebanyak 43 resep terdapat 14 resep yang berpotensi mengalami interaksi obat dimana tingkat signifikansi interaksi obat paling banyak yaitu level moderate (94,4%) selanjutnya pada level mayor (5,6%). Interaksi obat paling banyak yaitu pada interaksi antara Azitromisin dengan atorvastatin sebanyak 9 pasien yang tergolong interaksi moderate (50%), selanjutnya pada interaksi azitromisin dengan simvastatin dan azitromisin dengan rivaroxaban sebanyak 4 pasien yang tergolong interaksi moderate (22,2%) serta interaksi azitromisin dan amiodaron sebanyak 1 pasien yang tergolong interaksi mayor (5,6%). Jenis obat covid-19 yang paling sering digunakan yaitu Azitromisin (13,5%) dan obat Kardiovaskuler paling sering digunakan adalah Furosemid (13,8%). ABSTRACT Drug interaction is the effect of a drug caused when there are two or more drugs that interact and affect the body's response to treatment. This study is a descriptive study using a non-experimental observational method with a cross-sectional approach using retrospective observation by taking data in December 2020 - August 2021. Patient data collection was obtained from patient medical record data with a sampling technique that is purposive sampling with inclusion criteria as much as 43 patients were taken as samples. Data analysis using medscape and drugs.com applications. A total of 43 prescriptions there are 14 prescriptions that have the potential to experience drug interactions where the highest level of drug interaction significance is the moderate level (94.4%) then the major level (5.6%). The most drug interactions were the interactions between Azithromycin and atorvastatin as many as 9 patients classified as moderate interactions (50%), then the interactions between azithromycin with simvastatin and azithromycin with rivaroxaban were 4 patients classified as moderate interactions (22.2%) and the interactions between azithromycin and amiodarone in 1 patient classified as a major interaction (5.6%). The most frequently used type of Covid-19 drug was Azithromycin (13.5%) and the most frequently used Cardiovascular drug was Furosemide (13.8%)
| Item Type: | Thesis ( Diploma Tiga (D3)) | ||||||||||||
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| Uncontrolled Keywords: | Interaksi Obat, Azitromisin Covid-19, Kardiovaskuler, Azitromisin; Drug Interaction, Azithromycin Covid-19, Cardiovascular, Azithromycin | ||||||||||||
| Divisions: | Pharmacy Study Program | ||||||||||||
| Depositing User: | Yacobus Sudaryono | ||||||||||||
| Date Deposited: | 06 Oct 2022 02:05 | ||||||||||||
| Last Modified: | 23 Aug 2023 05:50 | ||||||||||||
| URI: | http://repository.itsk-soepraoen.ac.id/id/eprint/719 |
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