FORMULASI DAN UJI STABILITAS FISIK TABLET KEMPA EKSTRAK DAUN PEPAYA ( CARICA PAPAYA. L)

Sekti, Beta Herilla and Permata, Agung and Oktadiva, Neysa (2022) FORMULASI DAN UJI STABILITAS FISIK TABLET KEMPA EKSTRAK DAUN PEPAYA ( CARICA PAPAYA. L). Jurnal Herbal dan Farmakologis (HERBAPHARMA), 4 (1). pp. 53-61. ISSN 2722-709X

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Abstract

Daun Pepaya (Carica Papaya L.) merupakan tanaman yang memiliki kandungan alkaloid, flavonoid, tripertinoid, saponin dan tannin yang berguna untuk mengobati diabetes. Penelitian ini bertujuan untuk mendapatkan tablet kempa ekstrak daun pepaya dan mengetahui pengaruh konsentrasi pvp k30 sebagai bahan pengikat terhadap sifat fisik tablet kempa. Penelitian menggunakan metode eksperimental, dengan perbandingan formula 1 = 1 %, formula 2 = 3% dan formula 3 = 5% dan diuji sifat fisik tablet. Hasil penelitian didapatkan bahwa tablet memenuhi persyaratan dan hanya satu formula yang tidak memenuhi uji kerapuhan tablet. Kesimpulan penelitian tablet kempa ekstrak daun pepaya dengan perbedaan konsentrasi PVP K30 sebagai bahan pengikat memenuhi syarat untuk uji fisik tablet. ABSTRACT Papaya leaf (Carica Papaya L.) is a plant that contains alkaloids, flavonoids, tripertinoids, saponins and tannins that are useful for treating diabetes. This study aims to obtain compressed tablets of papaya leaf extract and determine the effect of the concentration of PVP K30 as a binder on the physical properties of compressed tablets. The study used an experimental method, with a comparison of formula 1 = 1%, formula 2 = 3% and formula 3 = 5% and tested the physical properties of tablets. The results showed that the tablets met the requirements and only one formula did not meet the tablet friability test. The conclusion of the research on compressed tablets of papaya leaf extract with different concentrations of PVPK30 as a binder met the requirements for the physical test of tablets.

Item Type: Article
Contributors:
ContributionNameNIDN / NIDKEmail
ReviewerAdianingsih, Oktavia RahayuNIDN0019109201UNSPECIFIED
ReviewerSamodra, GalihNIDN0607089301UNSPECIFIED
Uncontrolled Keywords: Daun pepaya (Carica Papaya. L), Tablet Kempa, Evaluasi Mutu Fisik Tablet; Papaya leaf (Carica Papaya.L), tablet compression, physical quality evaluation of tablets.
Divisions: Pharmacy Study Program
Depositing User: Yacobus Sudaryono
Date Deposited: 06 Jul 2022 07:01
Last Modified: 04 Sep 2023 03:02
URI: http://repository.itsk-soepraoen.ac.id/id/eprint/707

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